By J. T. Fitzsimons (auth.), G. Peters, J. T. Fitzsimons, L. Peters-Haefeli (eds.)

ISBN-10: 364261907X

ISBN-13: 9783642619076

ISBN-10: 3642619096

ISBN-13: 9783642619090

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A high plasma vpr level also increased the central blood volume by 30-40%. No spontaneous drinking was observed in dogs infused with vasopressin in the absence of an osmotic stimulus. /min (SZCZEPANSKA-SADOWSKA, FITZSIMONS, KOZLOWSKI, and SOBOCINSKA, unpublished data). The results are presented in Fig. 12 a. It appears that vasopressin given directly into the brain also influences the osmotic reactivity of the thirst mechanism. /min. A slight increase of the thirst threshold was observed in some cases with the highest rate of infusion.

44, 371-384 (1972). WOLF, A. : Osmometric analysis ofthirst in man and dog. Am. J. Physiol. 161,75-86 (1950). 35 A Radioimmunoassay for Plasma Antidiuretic Hormone and Its Application in a Case of Hypopituitarism Associated with a Loss of Thirst J. J. MORTON, J. J. BROWN, R. H. and J. 1. S. ROBERTSON CHINN, Introductiou A sensitive and specific radioimmunoassay for the estimation of plasma antidiuretic hormone and its use in a case of hypopituitarism with diabetes insipidus associated with a loss of thirst, is described in this chapter.

On the thirst threshold to osmotic stimuli. /ml. /ml. 001) (Fig. 9). This decrease was proportional to the increase in plasma vpr as shown in Fig. 10. However, the thirst threshold failed to decrease at very high plasma vpr levels (Fig. 11). equiv rt 60 vpr 40 r+ 20 o L - - . L . 001 Fig. 9. /ml. 100 '0 ... ) '- 0 ~ .. '. 80 60 40 Z 20 10 0 .. 78 x .. /ml. 40 50 Fig. 10. OOl Fig. 11. ) and vagosympathectomized (right side - VS) dogs. /ml. /ml. This rise in threshold could be partially prevented by left cervical vagosympathectomy.

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Control Mechanisms of Drinking by J. T. Fitzsimons (auth.), G. Peters, J. T. Fitzsimons, L. Peters-Haefeli (eds.)


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