By Ellen S. Vitetta

ISBN-10: 0127223800

ISBN-13: 9780127223803

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Pappenheim, X 2000 FIGURE 9. Frozen section of T-zone lymphana inmunostained with OIcr'11. All turror cells are positive, whereas cells of a residual follicle (upper right) are negative. X 300 2 MORPHOLOGY, CYTOCHEMISTRY, AND IMMUNOHISTOLOGY 21 Giant cells may be found in any of the variants. These cells sooetimes resemble Sternberg-Reed cells; others are nnlltilobulated. The results of imnunohistologic staining with nonoclonal antibodies in plearorphic T-cell lyrrphana are shown in Table 3. The T-cell nature of each case was daoonstrated by staining with OIcr'11 (Fig.

10) was diagnosed on a cervical lymph node biopsy in 1971 and again on a biopsy of subcutaneous tissue in 1974. The patient received ALL chenotherapy (Pinkel and Riehm regines), and the tunor disappeared. Three years later (1977) there was recurrence in inguinal lymph nodes. The new lesion showed a completely different picture, namely, the small cellular, plearorphic picture of Tcell lymphana (Fig. 11). The patient received ALL therapy and radiotherapy. , 5 years later, he is free of disease and may have been cured.

9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 41 In: B Lymphocytes in The Immune Response: Functional, Developmental, and Interactive Properties. Ed. N. Klinman, D. Mosier, I. Scher, and E. Vitetta, Elsevier North Holland, NY p. 141. , Stewart, C. , and Schlesinger, S. (1978). J. Exp. Med. 147:1253. Stewart, C. C. (1981) In: Methods for Studying Mononuclear Phagocytes, Academic Press, NY, p. 21. Warner, N. , Daley, M. , and Spellman, C. (1979). Immunol. Rev. 48:197. Lanier, L. , Warner, N.

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B and T Cell Tumors by Ellen S. Vitetta


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